Dr. Gundry Podcast

395: The Best Time to Take Supplements: What Actually Matters

Dr. Steven Gundry | March 17, 2026

If you’ve ever stood in the supplement aisle wondering which ones actually work, or whether you’re even taking them the right way, you’re not alone.

I get questions about supplements every single day. Should you take them with food or on an empty stomach? Does timing really matter? Do they break a fast? And how can you tell if the supplement you’re buying is actually high quality?

In this episode, I’m answering some of the most common supplement questions I hear from patients and listeners.

We break down what really matters when it comes to getting the most benefit from your supplements, and how to make sure the ones you’re taking are truly supporting your health.

On this episode, you’ll learn:

Best to spread your supplements out during the day? Or, take them all at once? (0:20)
If you can take supplements with alcohol (2:00)
Whether or not taking supplements breaks your fast (2:20)
How to know if you are getting high-quality supplements (3:30)
Why food alone often isn’t enough to meet your nutrient needs today (5:50)

The content is for general informational purposes only and does not constitute medical advice.

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