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364: GABA vs. Glutamate: the real brain battle

by | Aug 12, 2025 | 0 comments

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If you’re struggling with anxiety, poor sleep, or constant burnout — the problem might not be in your head… but in your brain chemistry.

In this episode, I’m joined by Dr. Scott Sherr, a board-certified internal medicine doctor and expert in integrative and hyperbaric medicine. He’s shining a light on a little-known brain chemical called GABA — often described as your brain’s “off switch.”

Dr. Sherr believes GABA deficiency is one of the most overlooked drivers of mental fatigue, stress, and sleep issues today. And more importantly, he shares powerful, practical ways to support GABA naturally — beyond just popping supplements. We’re talking cutting-edge tools like medicinal mushrooms (a.k.a. fungiceuticals), targeted lifestyle shifts, and more.

On this episode, you’ll learn: 

  • The surprising “missing link” in modern brain health that almost no one is talking about (3:05)
  • How today’s fast-paced work culture is secretly shocking your nervous system — and why it matters for your long-term health (5:15)
  • The real culprit behind depression and anxiety (hint: it’s not what most doctors think) (7:11)
  • The key levels you should ask your doctor to check at your next visit to protect your brain and body (9:45)
  • The little-known warning sign you might have “leaky brain” (and why you should never ignore it) (23:05)
  • If the new “mocktail” trend is really as healthy as it sounds — or just another wellness fad (23:45)
  • The brain-supporting compounds you can start eating today to boost your GABA naturally (29:10)
  • Why popping GABA supplements could backfire — and the smarter way to help your brain make its own (33:05)

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If you liked this episode, you may enjoy:

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Episode Transcript:

https://drgundry.com/ep-364-transcript/

Watch on YouTube:

Dr Gundry’s 4 ESSENTIAL Health Pillars to LIVE LONGER and Happier!

Your brain is changing (here’s why it matters) | Ep139

Dr. Gundry Reveals The ENERGY Habits That Will CHANGE Your Life!

LONGEVITY: What To Eat On ONE MEAL A Day! | Dr. Steven Gundry

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About Dr. Gundry

Dr. Steven Gundry is a renowned heart surgeon and New York Times bestselling author of “The Plant Paradox” and “The Plant Paradox Cookbook.”

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